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Therefore, an approach using the selective approach of stone-dissolution capsules will help to develop alternative urolithiasis treatments to the conventional surgical and systemic dissolution approaches.Simplicity Studio is the unified development environment for all Silicon Labs technologies, SoCs, and modules. In the end, more than 50% of stone, even in surgically tricky regions, was removed by 10 repeated treatments. Eventually, the potential removal of urolithiasis in the body was verified using a PDMS-based ureter-imitated chip with a human kidney stone (CaOx 100%, 5–7 mm size) was located in the minor calyx under an artificial urine counter flow (0.5 mL min−1).
Using a double-droplet microfluidics method, hexametaphosphate (HMP) chelating solution was encapsulated in an Fe3O4 nanoparticle (Fe3O4 NP)-loaded PLGA polymer shell with a thickness of 90%), and an effective removal efficacy (>95 %, 7 repeat cycles) of artificial calcium oxalate (5 mm in size) via a chelating effect. A novel urolithiasis treatment in which chelating solution encapsulated in poly(lactic-co-glycolic acid PLGA)-based microcapsules was delivered magnetically to specific urolithiasis sites and then subjected to ultrasound (US) to release the chelating solution and dissolve the stones.
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